Discover the most effective fish antibiotics for treating a wide range of aquarium infections — no prescription required. Whether you're dealing with fin rot, cloudy eyes, ulcers, or swim bladder issues, our selection of premium fish antibiotics ensures rapid recovery and long-lasting results. All medications are labeled for ornamental fish use and ship fast from the U.S.
Fish Mox (Amoxicillin):
A powerful broad-spectrum antibiotic used to treat bacterial infections including fin rot, popeye, body ulcers, and red streaks. It’s one of the most trusted first-line treatments for gram-positive infections.
Fish Flex (Cephalexin):
Commonly used for skin infections, open wounds, and tail rot. Cephalexin is ideal for gram-positive bacteria and is popular for its fast-acting recovery results.
Fish Flox (Ciprofloxacin):
Best for gram-negative bacterial infections such as cloudy eyes, gill issues, and internal infections. Highly effective in treating difficult conditions like columnaris and septicemia.
Fish Doxy (Doxycycline):
Useful for treating swim bladder infections, internal organ inflammation, and other resistant infections. Often recommended when other antibiotics fail.
Fish Zole (Metronidazole):
A go-to antifungal and antiprotozoal medication. Treats hole-in-the-head disease, hexamita, and internal parasites in tropical and freshwater fish.
Fish Sulfa (Sulfamethoxazole/Trimethoprim):
Excellent for treating respiratory infections, mouth fungus, and skin wounds. Offers broad-spectrum coverage and is especially effective in combination therapies.
Fish Cin (Clindamycin):
Used to manage anaerobic bacterial infections, including those causing deep-tissue wounds and internal abscesses. Ideal for more severe or advanced infections.
Fish Pen (Penicillin):
Highly effective against gram-positive bacterial infections. Treats tail rot, open sores, and gill issues with low risk of resistance.
Fish zithro (Azithromycin):
known for treating fin rot, cloudy eyes, and mild gill disease. Works well in early-stage infections and is gentle on sensitive fish.
Fish Fluconazole:
An antifungal treatment used to combat cottony patches, body fungus, and persistent fungal outbreaks in planted or soft-water tanks.
1. Do I need a prescription to buy fish antibiotics?
No. All our antibiotics are available over the counter and labeled for ornamental fish use only.
2. Are these the same as human antibiotics?
Yes, they contain the exact same active ingredients, but are labeled for fish to comply with OTC regulations.
3. Can I use these in a reef tank?
We recommend isolating infected fish in a hospital tank. Some antibiotics may impact beneficial bacteria in reef systems.
4. What is the best fish antibiotic for fin rot?
Fish Mox (Amoxicillin) and Fish Flex (Cephalexin) are the top choices for treating fin rot quickly and safely.
5. How do I dose fish antibiotics?
Each product includes instructions, but dosing is generally based on gallons of water. For example, Fish Mox may require one capsule per 10 gallons daily.
6. Are fish antibiotics safe for all ornamental fish?
Yes, when used properly and dosed according to instructions. Monitor water conditions during treatment.
7. How long should treatment last?
Most treatments run 5 to 10 days. Water changes between doses are strongly recommended.
8. Will the antibiotics turn the water cloudy or yellow?
Some products like Fish Zole or Fish Fungus may discolor the water temporarily. A charcoal filter will help clear it.
9. Do you offer fast shipping?
Yes. We ship from within the U.S. and most orders arrive within 2–5 business days.
10. What if there’s no improvement in 5 days?
Discontinue treatment and try an alternative antibiotic. Always complete the full course if improvement is seen.
11. Can I store unused antibiotics for later use?
Yes. Store in a cool, dry place away from sunlight. Do not use if tablets become discolored or damaged.
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